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KMID : 1035620140020030222
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Allergy Asthma & Respiratory Disease
2014 Volume.2 No. 3 p.222 ~ p.226
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Eosinophilic cholecystitis: A rare manifestation of hypereosinophilic syndrome
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Park Jae-Hyun
Kim Byoung-Hoon
Kim Mi-Kang
Lee Jae-Eun
Kim Kwang-Taek
Yoo Jun-Jae
Kim Hee-Jun
Jung Sung-Won
Kim Cheol-Hong
Hyun In-Gyu
Choi Jeong-Hee
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Abstract
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Eosinophilic cholecystitis (EC) is a rare form of acute cholecystitis, of which diagnosis is based on classical symptoms of cholecystitis with a presence of >90% eosinophilic infiltration within the gall bladder. EC rarely manifests in idiopathic hypereosinophilic syndrome (IHES). Here, we report two cases of EC with IHES. One is a 57-year-old male who presented with acute right upper quadrant (RUQ) pain, jaundice and fever. The initial peripheral blood eosinophil count was 2,070/mm3, and further elevated to 12,590/mm3. Acute acalculous cholecystitis with cholangitis was confirmed by computed tomography (CT). He improved with endocopic nasobiliary drainage and antibiotic therapy. The other is a 64-year-old female who presented with acute RUQ pain. She also complained of dyspnea and tingling sensation of both hands and feet. The initial peripheral blood eosinophil count was 10,400/mm3. Abdominal CT revealed findings suggestive of acute acalculous cholecystitis. She improved with systemic glucocorticosteroid therapy. No other causes of hypereosinophilia were found in either patients. Thus, cholecystectomy may not be mandatory for the treatment of EC with IHES.
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KEYWORD
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Hypereosinophilic syndrome, Cholecystitis, Cholangitis
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